Utilization of prophylactic drugs for covid-19 infection among health care workers at government medical college Srinagar-a retrospective observational study

Introduction: Corona virus disease (COVID-19) was declared as a Pandemic by WHO on March 11, 2020. Since health care workers play an important role in providing care to infected patients, they are exposed to unprecedented levels of risk. At the initial phase of this pandemic, no definitive treatment was available, the only way to combat this disease was prevention. A number of prophylactic drugs were being studied during that time for use by health care workers. On 23rd March 2020, Government of India issued recommendation through National Task Force for Covid-19, for using Hydroxychloroquine as prophylaxis for SARS COV-2. Preclinical studies of Azithromycin have shown immunomodulation and in vitro activity against SARS-COV-2, that has led to its widespread usage during COVID-19. Ivermectin, an antiparasitic drug was reported to have an in vitro activity against SARS-COV-2. This orally administered drug was included in India's revised National COVID-19 treatment protocol for people with mild infection. Vitamin C, a water soluble vitamin has been considered for potential beneficial effects in COVID-19 disease. Many animal studies have indicated that a daily intake of vitamin C may prevent infections. Aim(s): To evaluate the pattern of drugs (HCQ, AZITHROMYCIN, IVERMECTIN,and VITAMIN C) used for COVID-19 prophylaxis among health care workers at GMC, Srinagar. MATERIALS AND METHODS: This study is being conducted by using a survey questionnaire. A survey questionnaire in English has been developed after literature review. The responses will be analyzed using descriptive statistics of frequency and percentage.

Experience of distance learning during COVID-19 pandemic among undergraduate nursing students

COVID-19 Pandemic has a huge influence on the learning process worldwide. To maintain student academic progress, learning activities were converted to distance learning to control the further spread of the COVID-19 virus. During this period several studies around the world were conducted to assess the effectiveness of distance learning. The results of these studies showed different perspectives, some of the students preferred e-learning while other preferred traditional methods. The aim of this study was to assess the experience of undergraduate nursing students who used distance learning during the COVID-19 pandemic. A quantitative, cross-sectional design was used to conduct the study. A convenient sampling approach was used to collect the data electronically via self-reported questionnaires. The study included 328 participants. The average score of the effectiveness domain was (2.58 +/- 0.68, medium level), and the satisfaction domain was (2.56 +/- 0.54, medium level). The results indicate that technical issues were the most significant barrier (75.6%) to distance learning, followed by physical problems, and decreased access to technological devices. Savings in transportation costs (74.1%), savings in time (71.6%), and the opportunity to review recorded lectures (67.4%) were the benefits of distance learning reported by nursing students during the COVID-19 pandemic. Most of the nursing students reported a positive preference for distance learning. Technical issues were the most significant barrier while decreased transportation costs were the most significant facilitator. These findings were consistent with other studies from different settings. Further research is needed to build upon these findings. (C) 2022 The Authors. Published by IASE.

Occurrence of Bacterial Conjunctivitis and Viral Conjunctivitis in Pakistan

Aim: To identify the prevalence of bacterial and viral conjunctivitis. Study design: Prospective study. Place and Duration of Study: Department of Ophthalmology, Pakistan Railways Hospital, Islamic International Medical College, Rawalpindi from 1st April 2021 to 30th September 2021. Methodology: Fifty conjunctivitis patients enrolled within age of 14-29 years. Clinical examination, slit lamp test and lab testing separated cases as viral or bacterial conjunctivitis. Polymerase chain reaction post culturing was sued in viral conjunctivitis cases while Kirby-Baur disc diffusion assay was sued in bacterial conjunctivitis confirmation. Results: There were 91.17% patients with viral conjunctivitis in age of 24-29 years and 62.5% patients with bacterial conjunctivitis within 14-18 years. The odds ratio value between the male and female gender showed a significant difference between both genders with 95% confidence interval with higher female frequency in both. Coronavirus cases were highest with 52.9% while cases of Micrococciwere highest as 37.5% with conjunctivitis. Conclusion: Viral conjunctivitis was more common in general cases due to recent covid-19 infection followed by Micrococci bacterial conjunctivitis.

Closed Formulas of Topological Properties for Remdesivir (C27H35N6O8P)

Coronavirus is able to cause illnesses ranging from the common flu to severe respiratory disease. Today there is great competition among researchers and physcisians to cure COVID-19. Remdesivir is being studied for the COVID-19 treatment In this article, we presented the topological analysis of remdesivir with the help of M-polynomial. Proofs of the closed form of some topological indices via M-polynomial are also included in this article. [GRAPHICS] .